ppat.1009889.s003.tif (649.9 kB)
Expression of FTH1 in Huh-7 cells after HCV infection.
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posted on 2021-09-07, 17:48 authored by Bei Wang, Yue Zhu, Congci Yu, Chongyang Zhang, Qing Tang, He Huang, Zhendong ZhaoHuh-7 cells were infected with HCV (MOI = 1). The protein level of FTH1 was analyzed by western blotting. HeLa cells were transfected with GFP-, FTH1-, or Flag-tagged FTH1 (as the positive controls for FTH1). Actin was used as the loading control. * Nonspecific bands
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repressed viral assemblycellular lipid contentapob required derlinapob may contributeenhance lipid accumulationenhanced hcv assemblydecreased lipoprotein secretioninduced apob degradationlipid accumulationcontaining lipoproteininduced degradationhcv inducedoxidized apobapob levelapob degradationapob ).psma6 subunitsinfection inducesinfection increasedinfected cellsindependent mannerimpaired productionhepatic steatosishcv infectionendoplasmic reticulumcompletely elucidatedautophagic degradationapolipoprotein b
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