pntd.0009719.g006.tif (855.29 kB)
Evolutionary relationships in the Trypanosoma cruzi complex.
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posted on 2021-08-26, 17:51 authored by Luisa Berná, Gonzalo Greif, Sebastián Pita, Paula Faral-Tello, Florencia Díaz-Viraqué, Rita De Cássia Moreira De Souza, Gustavo Adolfo Vallejo, Fernando Alvarez-Valin, Carlos RobelloT. cruzi is composed by two main groups 1 and 2, which does not correspond to the original I and II groups. Group 1 is divided in clades A, B and D, and group 2 contains clade C. Lower cases indicate the maxicircle variant (a, b, and c), and BC refers to hybrid strains.
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reinforcing biochemical findingsreal lengths rangenadh dehydrogenase subunitsdiv >< pcareful phylogenetic analysiscontaining clade cspecies evolutionary diversitymaxicircle variants presentcommon architecture composedstrains lead ustrypanosoma cruzi tci ), bc carry maxicirclesspecies composedmaxicircle architecturethree variantsphylogenetic relationshipsevolutionary insightscruzi allowed ustciv ),tcii ),strains representativehybrid strainscr ),c respectively29 strainsusing longstrand orientationsequenced maxicirclesrich regionrepetitive regionsread sequencingnew nomenclaturemitochondrial phylogeniesmaxicircles existmakes usemain differenceslr ).long repeatsfour regionscoding regionclearly establishingbc type50 kb
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