ppat.1009994.s003.tif (522 kB)
Evaluation of BoNT/B and BoNT/G using DAS assays on WT and Syt1M3 mice.
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posted on 2021-10-18, 18:27 authored by Hatim Thaker, Jie Zhang, Shin-Ichiro Miyashita, Vivian Cristofaro, SunHyun Park, Ali Hashemi Gheinani, Maryrose P. Sullivan, Rosalyn M. Adam, Min DongA. The indicated doses of BoNT/B were used in DAS assays and the scores over time were plotted. B. The indicated doses of BoNT/G were used in DAS assays and the scores over time were plotted.
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wild type micetarget neurons determinesskeletal neuromuscular junctionspotent toxins knowndominant toxin receptorbonts &# 8217analyzing bont actiondominant receptorinjecting toxinswide rangetwo setstherapeutic efficacyoveractive bladderleg musclefindings establishcritical rolebladder tissuesalso utilized
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