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Embryonic lethality of homozygous knockout mice of Pgam1.

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posted on 2021-04-29, 17:29 authored by Takumi Mikawa, Eri Shibata, Midori Shimada, Ken Ito, Tomiko Ito, Hiroaki Kanda, Keiyo Takubo, Atsuyoshi Shimada, Matilde E. Lleonart, Nobuya Inagaki, Masayuki Yokode, Hiroshi Kondoh

(A) Summary of Pgam1 genotypes for 155 progenies from crosses between Pgam1+/− mice. +/+; wild-type, +/−; heterozygous KO, −/−; homozygous KO. (B) Summary of Pgam1 genotypes for embryo from crossing between Pgam1+/− mice at embryonic day 13.5 (E13.5). (C) Schematic diagram of glycolytic pathway. (+) indicates embryonic lethality in homozygous knockout mice, as reported previously (ref. [2125]).

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