Fig 3.tif (95.74 kB)

Effects of claudin-2, occludin or ZO-1 siRNA transfection on transepithelial electrical resistance (TER) in HK-2 cell monolayers.

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posted on 2017-12-18, 18:32 authored by Sua Kim, Gheun-Ho Kim

TER was significantly decreased by claudin-2 siRNA transfection, but significantly increased by siRNA transfection against occludin or ZO-1. Data are means ± SD. *P < 0.05 by Student’s t-test for unpaired data.

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claudin -2 expression tubule epithelial cell line HK -2.claudin -2 ZO RNA HK -2 cells control HK -2 monolayers TJ protein expression TER occludin siRNA Dextran flux rate transepithelial flux rates paracellular permeability

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