pone.0256973.g008.tif (121.82 kB)
Effect of miR-181c overexpression in liver on insulin secretion.
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posted on 2021-12-08, 18:30 authored by Kei Akiyoshi, Gretha J. Boersma, Miranda D. Johnson, Fernanda Carrizo Velasquez, Brittany Dunkerly-Eyring, Shannon O’Brien, Atsushi Yamaguchi, Charles Steenbergen, Kellie L. K. Tamashiro, Samarjit Das(A) Body weight. (B) Blood glucose and area under the curve during an IPGTT. (C) Plasma insulin levels and area under the curve during an IPGTT. OE, overexpression; Scr, scrambled oligonucleotide. Data are expressed as mean ± SEM; n = 8 per group. *p<0.05 by Bonferroni post hoc analysis after intergroup differences were found by 2-way ANOVA.
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sup >-/-pathophysiological complications associatedisocitrate dehydrogenase 1indirect calorimetric measurementsassociated virus attenuatedseveral genes regulatedinduced cardiac dysfunctiondiv >< pliver triglyceride levels181c might contributelipid synthesis genesqpcr data showedliver wt mice fedlipid synthesisgenes involvedvivo data indicatewt liverliver playsinduced obesityvia adenotaken togetherrecently identifiedquantitative pcrmitochondrial pathwaymice fedmetabolic consequencesinsulin insensitivityhigher serumencoded mirna26 weeks181c delivered
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