Effect of HRI activators on USUV multiplication.

(A) Cell viability was determined as ATP content in mock-infected cells treated with the drugs at 24 and 48 h. The dotted line indicates 80% of the viability of control cells; (B) Cells were infected with an MOI of 1 PFU/cell, and 24 or 48 h p.i. were treated with ArsNa (0.5 mM), or BTdCPU (20 μM) for 4 hours. Then, virus yields in culture supernatants were determined by plaque assay. Data represent the average of three independent experiments.