pone.0254972.g002.tif (311.01 kB)
Dot plots of immune mediators, IL-1β, IL-6, IFN-γ and TNF-α. IL-1β, IL-6, IFN-γ and TNF-α in serum of noninflammatory controls patients (cataract age-related) (CTL) (N = 36) as compared with immune mediators in the serum of patients with idiopathic uveitis (n = 51) but differences in both groups are not significant.
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posted on 2022-01-21, 18:39 authored by Marie-Hélène Errera, Ana Pratas, Sylvain Fisson, Thomas Manicom, Marouane Boubaya, Neila Sedira, Emmanuel Héron, Lilia Merabet, Alfred Kobal, Vincent Levy, Jean-Michel Warnet, Christine Chaumeil, Françoise Brignole-Baudouin, José-Alain Sahel, Pablo Goldschmidt, Bahram Bodaghi, Coralie Bloch-QueyratNote that few isolated patients with idiopathic uveitis had cytokines increased in serum samples. * = P<0.05; ** = P<0.01; *** = P<0.001.
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whether cytokine profilestnf -&# 945immune mediator expressionhigh expression levelshierarchical unsupervised classificationcontrol group consistedcombined data suggestclustered 4 subgroupsbeh &# 231intraocular fluid analysesnoninfectious controls consistedinfectious controls consistedhuman aqueous humorgrowth factors profilesarcoidosis related uveitisidiopathic uveitis usingpredominantly proinflammatory cytokinesgrowth factorsaqueous humoridiopathic uveitisrelated cataractintraocular cytokinesxlink ">vascular mediatorsth17 pathwaysstatistical analysissignificantly elevatedocular toxoplasmosisobvious thmultiplex immunoassayalso il975 patients7 patients29 mediators16 patients15 patients
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