pone.0254972.g004.tif (236.32 kB)
Dot plots of immune mediators: IL-10, IL-12, IL-17, G-CSF, in aqueous humor of patients with idiopathic uveitis (N = 64) as compared with immune mediators in the aqueous humor of noninflammatory controls patients (cataract age-related) (N = 36).
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posted on 2022-01-21, 18:39 authored by Marie-Hélène Errera, Ana Pratas, Sylvain Fisson, Thomas Manicom, Marouane Boubaya, Neila Sedira, Emmanuel Héron, Lilia Merabet, Alfred Kobal, Vincent Levy, Jean-Michel Warnet, Christine Chaumeil, Françoise Brignole-Baudouin, José-Alain Sahel, Pablo Goldschmidt, Bahram Bodaghi, Coralie Bloch-QueyratNote that few isolated patients with idiopathic uveitis had an immune mediator elevated. * = P<0.05; ** = P<0.01; *** = P<0.001.
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whether cytokine profilestnf -&# 945immune mediator expressionhigh expression levelshierarchical unsupervised classificationcontrol group consistedcombined data suggestclustered 4 subgroupsbeh &# 231intraocular fluid analysesnoninfectious controls consistedinfectious controls consistedhuman aqueous humorgrowth factors profilesarcoidosis related uveitisidiopathic uveitis usingpredominantly proinflammatory cytokinesgrowth factorsaqueous humoridiopathic uveitisrelated cataractintraocular cytokinesxlink ">vascular mediatorsth17 pathwaysstatistical analysissignificantly elevatedocular toxoplasmosisobvious thmultiplex immunoassayalso il975 patients7 patients29 mediators16 patients15 patients
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