pone.0294282.g002.tif (1.28 MB)
Differential expressed aging-related genes in AF and SR samples.
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posted on 2023-11-13, 18:30 authored by Yong Zhou, Chao Sun, Yingxu Ma, Yunyin Huang, Keke Wu, Shengyuan Huang, Qiuzhen Lin, Jiayi Zhu, Zuodong Ning, Ningyuan Liu, Tao Tu, Qiming Liu(A) Venn plot of overlapped genes between DEGs from metadata cohort and 307 aging-related genes from Human Aging Genomic Resource. The intersected 24 genes were considered aging-related DEGs. (B)Volcano plot of 24 differential expressed aging-related DEGs. (C)Box plot of 24 differentially expressed aging-related genes in AF and SR samples. *p<0.05, **p<0.01, ***p<0.001, ****p<0.0001.
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longevity regulating pathwaykegg enrichment analysesfoxo signaling pathwayakt signaling pathwayinfiltrating immune cellsimmune cell infiltratesfunctional enrichment analysisleft atrial samplesestimate immune infiltrationcorrelation analysis revealeddifferential expression analysisdiv >< ppotential diagnostic biomarkersrelated genes associatedimmune infiltrationcorrelation analysisdiagnostic potentialatrial fibrillationscreened genesrelated genesmrna expressionexpression levelspotential agingtxn transcriptome profilessod2 significant roleroc curvesperoxisome accordingmcc algorithmsmay playmainly involvedhspa9 geo databaseessential role
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