pntd.0009924.g001.tif (56.02 kB)

Difference in outcome measure of the assays between paucibacillary and multibacillary patients as per WHO operational classification.

figure

posted on 2021-11-10, 18:25 authored by Sofie Marijke Braet, Anouk van Hooij, Epco Hasker, Erik Fransen, Abdou Wirdane, Abdallah Baco, Saverio Grillone, Nimer Ortuno-Gutierrez, Younoussa Assoumani, Aboubacar Mzembaba, Paul Corstjens, Leen Rigouts, Annemieke Geluk, Bouke Catherine de Jong

(A) Outcome measure of RLEP-qPCR on skin biopsies as determined by the bacterial load in a 4mm skin biopsy of paucibacillary and multibacillary patients as per WHO operational classification. (B) Outcome measure of RLEP-qPCR as determined by the bacterial load in nasal swabs of paucibacillary and multibacillary patients. (C) Outcome measure of the αPGL-I test on fingerstick blood as measured by ratio (R) value, being relative fluorescence units measured at test line divided by the signal measured at the flow-control line of paucibacillary and multibacillary patients.