Deletions of ISU1, HOG1, GRE3 and IRA2 are sufficient to increase cell growth and xylose consumption rates.
Indicated strains were cultured in YPX media under aerobic (A-B) or anaerobic (C-F) conditions. Average growth and specific xylose consumption rates with standard deviations are reported in g of dry cell mass•hr-1 (A, C) or OD600•hr-1 (E), and g of xylose consumed•g of dry cell mass-1•h-1 (B, D) or g of xylose consumed•OD600-1•h-1 (F), respectively, from the indicated strains cultured in YPX media from three independent biological replicates. Asterisks denote statistically significant differences (*; P < 0.05, **; P < 0.061) between specified strains by paired Student’s t-test. Xylose consumption rates for all strains in (D) were significantly faster (P < 0.05) than Y22-3MR.