Delayed seizure development in LSL-RHEBp.P37L mice injected with tamoxifen.

Onset of seizure activity for the LSL-RHEBp.P37L groups after treatment with tamoxifen (4 injections) starting at either P7 (purple line, mean ± SEM: 50 days ± 0) or at P21 (yellow line, mean ± SEM: 74.6 days ± 4.37) compared to the RHEBp.P37L group (red line) (chi-squared (2) = 25.33, p < 0.0001; log-rank test; N indicates number of mice). The data underlying this figure can be found in S4 Data.

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