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Cytolytic activity of lymphocytes from healthy donors or breast cancer patients against the M74 cell line

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posted on 2011-12-31, 00:01 authored by Alban Gervais, Jean Levêque, Françoise Bouet-Toussaint, Florence Burtin, Thierry Lesimple, Laurent Sulpice, Jean-Jacques Patard, Noelle Genetet, Véronique Catros-Quemener

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Taken from "Dendritic cells are defective in breast cancer patients: a potential role for polyamine in this immunodeficiency"

Breast Cancer Research 2005;7(3):R326-R335.

Published online 25 Feb 2005

PMCID:PMC1143555.

Copyright © 2005 Gervais et al.; licensee BioMed Central Ltd

Lymphocytes are from donors (= 5) or from cancer patients (= 6), and were stimulated with autologous immature dendritic cells (DCs) pulsed with peroxide-treated M74 cells (DC-Tu). Controls are nonstimulated lymphocytes (NSL). Values are expressed as cytolytic activity (with standard error) against M74 target cell line. *< 0.03 versus NSL; < 0.05 versus corresponding donors.

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