ppat.1009030.s010.tif (322.19 kB)
Cytokine response in WT and PGLYRP1-/- mice.
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posted on 2020-11-11, 18:34 authored by Akash Gupta, Gunjan Arora, Connor E. Rosen, Zachary Kloos, Yongguo Cao, Jiri Cerny, Andaleeb Sajid, Dieuwertje Hoornstra, Maryna Golovchenko, Natalie Rudenko, Ulrike Munderloh, Joppe W. Hovius, Carmen J. Booth, Christine Jacobs-Wagner, Noah W. Palm, Aaron M. Ring, Erol FikrigThe infected PGLYRP1-/- mice also showed overall different levels (in pg/mL) of CXCL-1, MCP-1, MIP-1B, and MIP-2 (A) and TNF-α, IL-10, IL-4, IL-5, IL-10, IL-17 (B) as compared to BALB/c mice infected mice although the profiles were statistically insignificant. Representative results from one independent experiment are shown. Each data point represents an individual animal in the corresponding group. The bars represent mean ± SEM.
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exhibits borreliacidal activityPeptidoglycan Recognition Protein 1burgdorferi infectionspirochete Borrelia burgdorferiIFNburgdorferi sensu latosystems biology approachsecretome library screenDiverse host responses influenceCXCLyeast display screeningserum IgG levelsLyme borreliosis Lyme diseasePGLYRP 1yeast display library
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