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CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo-6
figure
posted on 2011-12-31, 11:02 authored by Pascal Knuefermann, Georg Baumgarten, Alexander Koch, Markus Schwederski, Markus Velten, Heidi Ehrentraut, Jan Mersmann, Rainer Meyer, Andreas Hoeft, Kai Zacharowski, Christian GrohéCopyright information:
Taken from "CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo"
http://respiratory-research.com/content/8/1/72
Respiratory Research 2007;8(1):72-72.
Published online 9 Oct 2007
PMCID:PMC2173891.
CpG-ODN challenge total cell counts were significantly higher in WT mice compared to TLR9-D animals (A). In WT animals a significant increase of neutrophils (PMNs) after CpG-ODN stimulation was observed (B), which was absent in TLR9-D mice (mean ± SEM; * < 0.05).