pone.0245382.s002.tif (1.25 MB)
Correlates of RBD:ACE-2 binding inhibition amongst cohort members demonstrating rapid humoral responses (<7 days).
figure
posted on 2021-01-26, 18:23 authored by Isa Murrell, Donall Forde, Wioleta Zelek, Linda Tyson, Lisa Chichester, Nicki Palmer, Rachel Jones, B. Paul Morgan, Catherine MooreThe relationship between anti-S1 IgG, anti-NP IgG or anti-RBD IgG development and sRBD:ACE-2 inhibition potency was investigated by Pearson’s correlation test and two-tailed p test. All y-axis are % RBD:ACE-2 inhibition reported by the sVNT assay, whilst x-axis are ratios for EuroImmun assay and Abbott assay, or OD readouts from the RBD IgG ELISA assay. r2 describes correlation coefficients. Abbreviations/symbols: ns = no significance; * = p ≤ 0.05; ** = p ≤ 0.01; *** p ≤ 0.001; **** p ≤ 0.0001.
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