ppat.1010121.s009.tif (2.17 MB)
Complete set of EsxA1 lipid bilayer traces and 2D class averages.
figure
posted on 2021-12-06, 18:33 authored by Brady L. Spencer, Uday Tak, Jéssica C. Mendonça, Prescilla E. Nagao, Michael Niederweis, Kelly S. DoranAdditional current traces of recombinant CJB111 EsxA1 pore formation in DphpC lipid bilayers at a) pH 7.4 and b) pH 4.0 in 25 mM sodium phosphate 1M KCl. c) Additional reference-free 2D class averages of negatively stained EsxA1 imaged by transmission electron microscopy.
(TIF)
History
Usage metrics
Categories
Keywords
secrete effector proteinslower bacterial burdensdiv >< pbioinformatic analysis indicatesparental gbs strainmycobacterial esxa homologt7ss induces cytotoxicityt7ss effector functionmediates cytotoxicitycytotoxicity phenotypest7ss machineryfunctional t7sswork revealsthus demonstratingstreptococcus murine modelmice infectedlxg motifsinterbacterial killinghost toxicityhematogenous meningitisgroup bgbs pathogenesisforming proteinesxa contributesdependent mannerdecreased inflammationbrain endotheliumbrain compared
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC