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Comparison of the total GPVI, GPVI-dimer, and P-selectin exposure in day-0 (no anti-platelets) and the same individuals at day-90 who were discharged on clopidogrel.

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posted on 2022-01-18, 18:33 authored by Isuru Induruwa, Harriet McKinney, Carly Kempster, Patrick Thomas, Joana Batista, Jean-Daniel Malcor, Arkadiusz Bonna, Joanne McGee, Elaine Bumanlag-Amis, Karola Rehnstrom, Sophie Ashford, Kenji Soejima, Willem Ouwehand, Richard Farndale, Kate Downes, Elizabeth Warburton, Masaaki Moroi, Stephanie Jung

GPVI-dimer was significantly increased (A, P = 0.007) but total GPVI was not (B, P = 0.68). Both resting P-selectin (C, P = 0.001) and ADP-induced P-selectin were significantly lower at day-90 (D, P = 0.002), but CRP-XL–induced P-selectin was not (E, P = 0.90). Error bars represent median (Q1-Q3) %PP. P-values calculated using a paired t-test for parametric or Wilcoxon signed-rank test for non-parametric data. ns = not significant.

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