pone.0298640.g002.tif (710.23 kB)
Comparison of the number of OMP-positive cells in the saline and CGF groups.
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posted on 2024-02-28, 18:31 authored by Naruhiko Kai, Naoya Nishida, Kunihide Aoishi, Taro Takagi, Naohito HatoLeft: Representative images of OMP immunostaining of the OE of the healthy, saline, and CGF groups on day 28 are shown. The square scale in the figure is 100 μm × 100 μm. The number of OMP-positive cells in this square scale was counted. Right: The number of OMP-positive cells of the CGF group is higher in the CGF group than in the saline group (P = 0.009). However, the value did not improve to the number of OMP-positive cells in the healthy group. CGF, concentrated growth factor; OE, olfactory epithelium; OMP, olfactory marker protein.
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concentrated growth factorsbehavioral assessments using90 ± 984 ± 429 ± 9olfactory marker proteinolfactory epithelial thicknesses64 ± 308 ± 300 ± 3significantly increased compared4 2 0 × 10olfactory dysfunction modelsaline group (<olfactory dysfunctionolfactory epitheliumsignificantly thickerrat modelimprovement comparedsaline groupcontrol groupp xlink ">two groupsstudy aimedsignificant differenceseven animalssaline groupssaline administrationregenerative capacityrandomly dividedintraperitoneally injectedintraperitoneal administrationintranasal administrationhistological evaluationgroups showedfive animalsday 28cell countavoidance test28 days013 ).009 ).
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