pone.0295053.s009.tif (159.03 kB)
Comparison of fold changes in gene expression between independent RNAseq (FC (RNAseq)) and Fluidigm (FC (Fldgm)) experiments using TNF-activated HBMEC co-cultured with IT4var14.
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posted on 2023-11-30, 19:06 authored by Basim Othman, Leo Zeef, Tadge Szestak, Zineb Rchiad, Janet Storm, Caroline Askonas, Rohit Satyam, Aymen Madkhali, Michael Haley, Simon Wagstaff, Kevin Couper, Arnab Pain, Alister CraigThe results shown are for 6 hours of co-culture. Outliers are marked with blue triangles and are not included in the regression analysis.
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pathways previously foundprotein called pfemp1human malaria specieshost immune systemdiv >< pinfected erythrocyte membranedifferent pfemp1 variantsplasmodium falciparum human malaria parasitedifferent pfemp1p falciparum severe malariamalaria infectioninfected erythrocyteserythrocytes infectedvascular endotheliumtranscriptional profilesevere diseasemorbidity causedhost microvasculatureendothelial receptorsdifferential engagementbarrier integrityadhesive domains
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