ppat.1011063.g002.tif (832.04 kB)
Comorbidities that may synergize with COVID-19 to predispose risks to PH.
figure
posted on 2023-01-12, 18:26 authored by Rahul Kumar, Öznur Aktay-Cetin, Vaughn Craddock, Daniel Morales-Cano, Djuro Kosanovic, Angel Cogolludo, Francisco Perez-Vizcaino, Sergey Avdeev, Ashok Kumar, Anil Kumar Ram, Stuti Agarwal, Ananya Chakraborty, Rajkumar Savai, Vinicio de Jesus Perez, Brian B. Graham, Ghazwan Butrous, Navneet K. DhillonThe possible interactions between long COVID state and preexisting comorbidities that may contribute to pulmonary vascular remodeling and the development of PH. Created with BioRender.com. COVID-19, Coronavirus Disease 2019; HIF1-α, hypoxia-inducible factor 1-alpha; PH, pulmonary hypertension; SARS-CoV-2, Severe Acute Respiratory Syndrome Coronavirus 2; TGF-β, transforming growth factor-beta.
History
Usage metrics
Categories
Keywords
past two yearsmolecular signals involvedmay consequently leadinvestigators accumulated evidenceemphasize recent updatescoronavirus disease 2019although targeting primarilycurrently available therapiesimmune responses associatedcomorbidities available therapyimmune systemimmune cellsxlink ">well establishedvirus triggersviral infectionterm effectsterm consequencessublineages posestructural cellsrespiratory systempulmonary vasculaturepathophysiological inflammatorynew challengeimmunized populationsendothelial dysfunctionelicited protectionefficiently spreadasymptomatic individuals
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC