pntd.0011770.g004.tif (351.39 kB)
Changes in cytokines levels secreted in rhesus macaque after immunization.
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posted on 2023-11-20, 18:37 authored by Hailong Su, Jun Liu, Jianhai Yu, Zhenzhen Qiu, Wenhan Liang, Wangsheng Wu, Haifeng Mo, Hongwei Li, Wei Zhao, Weiwang GuPre-immune PBMCs and those obtained at 4 weeks, 8 weeks, and 12 weeks after immunization from rhesus macaques were incubated with ZIKV E protein for 48 hours. Following incubation, culture supernatants were collected for flow cytometric assays. Three replications were done in each experiment and repeated three times. ****: P < 0.0001.
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obtained 293t cellslentiviral expression systemcause great harmfc effectively inducezika virus stably secreted ediiifc protein usingzika e proteinimmunized mice comparedzika viruse proteinfc proteinviral replicationsignificantly inhibitedrhesus macaquespregnant womenplacental barrierneutralizing antibodiesimmunized miceeven miscarriageediii regiondrug availablecell immunity
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