pgen.1009564.s012.tif (91.07 kB)
Cell-based assay results for 3M2H against other receptors in the A) OR51B2 and B) OR52A1 clusters.
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posted on 2022-02-03, 18:26 authored by Bingjie Li, Marissa L. Kamarck, Qianqian Peng, Fei-Ling Lim, Andreas Keller, Monique A. M. Smeets, Joel D. Mainland, Sijia WangNo receptors responded significantly above the vector control (Rho). Luciferase values were normalized by RL readings and then baselined to zero by subtracting the response of the no-odor control.
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two novel associationsstudy provides informationmultiple receptor typesimplying functional changesgives us insightethnically diverse populationdrive specific anosmia1000 han chineseamino acid substitutionsrepresent odor informationhuman underarm odorrobust across populationsodors containing aldehydesnovel musk receptorreduced odor intensityodor perception contributehuman body odorodor intensitybody odorodor perceptionhexenoic acidodor receptorsperception phenotypesfirst humanxlink ">wide scansvalidated resultsten odorssnps tendsnps detectedprevious studiesperformed genomeor2j3 ldolfactory phenotypemusk galaxolidemusk compoundkey componentgenotype studiesderived allelesdecoding olfactionbroader mechanismsband ),activity patterns364 ).
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