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CENP-E regulation

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posted on 2011-12-30, 17:13 authored by Frank Kullmann, Martin Judex, Wibke Ballhorn, Hans-Peter Jüsten, Dieter Wessinghage, John Welsh, Tim J Yen, Bernhard Lang, Jim C Hittle, Michael McClelland, Steffen Gay, Jürgen Schölmerich, Ulf Müller-Ladner

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Taken from "Kinesin-like protein CENP-E is upregulated in rheumatoid synovial fibroblasts"

Arthritis Research 1999;1(1):71-80.

Published online 26 Oct 1999

PMCID:PMC17776.

Copyright © 1999 Current Science Ltd

The figure shows CENP-E messenger RNA in CENP-E high (right lanes 3/4, 7/8, 11/12 and 15/16) and CENP-E low (left lanes 1/2, 5/6, 9/10 and 13/14) expressing rheumatoid arthritis synovial fibroblast populations after different prednisolone exposure (lanes 1–8) and serum starvation (lanes 9–12). As compared with unstimulated fibroblasts (lanes 13–16) no significant alteration in CENP-E messenger RNA expression, either in CENP-E high- or in CENP-E low-expressing fibroblast populations, can be observed after prednisolone exposure. Serum starvation was also not able to suppress CENP-E messenger RNA completely (lanes 9–12).

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