CD14 mediates peptidoglycan–polysaccharide complex (PG-PS)-induced secretion of IL-6 and tumor necrosis factor (TNF)-α
Taken from "CD14 mediates the innate immune responses to arthritopathogenic peptidoglycan–polysaccharide complexes of Gram-positive bacterial cell walls"
Arthritis Research & Therapy 2004;6(3):R273-R281.
Published online 27 Apr 2004
Copyright © 2004 Li et al.; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.Peritoneal macrophages were stimulated for 4 hours with the indicated concentrations of PG-PS. Concentrations of TNF-α and IL-6 were determined in supernatants by ELISA. Each determination was done in duplicates. TNF-α production by peritoneal macrophages. Data represent means ± standard error of the mean from three independent experiments. IL-6 production by peritoneal macrophages. Data represent mean ± SEM from two independent experiments.