pone.0298802.g003.tif (215.19 kB)
Biological categories of genes exhibiting differential expression in high outflow and low outflow regions of the TM.
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posted on 2024-02-23, 18:43 authored by Jennifer A. Faralli, Mark S. Filla, Yong-Feng Yang, Ying Ying Sun, Kassidy Johns, Kate E. Keller, Donna M. PetersBiological processes were identified through gene ontology enrichment analysis using the following databases: DAVID Bioinformatics Resources, Gene Cards and UniProt.
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α8 integrin subunittranscriptome analyses revealedlog2fc ± 1integrin signaling (<digital spatial profilingunderstanding segmental flowspatial transcriptomics approachimmunolabeling studies supporteddiv >< ptwo genes associatedlow outflow regionsdifferentially expressed genestrabecular meshwork revealssegmental outflow regionslargest differential expressionhigh outflow regionscell adhesion genesadam15 psegmental outflowtrabecular meshworkcell adhesionuseful approachdifferential expression57 genes16 genesldb3 crkl bgn adam15 thus demonstratingstudies showedsmall leucinesignal transductionschlemm ’key playersinner walleither highcrkl )
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