Associations of change in limb lean mass indices from age 10 y to 25 y with cardiometabolic traits at 25 y among Avon Longitudinal Study of Parents and Children Generation 1 individuals.

Estimates are beta coefficients and 95% CIs representing SD-unit differences in cardiometabolic traits at 25 y per SD-unit gain in lean mass index from 10 y to 25 y (based on standardised index at 25 y minus standardised index at 10 y). Models adjusted for age, sex, ethnicity, maternal education, lean mass index at 10 y, change in the other lean mass index, and change in total fat mass index (N range: 2,121 to 2,804). Limb lean mass index defined as sum of lean mass in arms and legs (kg) divided by squared height (m²). Apo, apolipoprotein; LDL, low-density lipoprotein; HDL, high-density lipoprotein; IDL, intermediate-density lipoprotein; VLDL, very-low-density lipoprotein.