Association of vacuolation, EIA, and immunohistochemistry data with results by sheep genotype and inoculum source.

This summary demonstrates differences between sheep of different genotypes challenged with the same inoculum (A-C received inoculum from deer cerebrum; D-F received inoculum from deer obex) and sheep of the same genotype challenged with different inocula. Each quadrant represents a brain region tested (brainstem at the level of the obex, cerebellar grey matter, cerebellar white matter, or neocortex). Each wedge in the quadrant is a different test (vacuolation, EIA, or IHC). The color of the wedge represents the severity of the results from each test, where lower scores received a lighter shade and higher scores received a darker shade. Negative assays are denoted in white. A) VRQ/VRQ with deer cerebrum represents sheep 1 and 2; B) ARQ/ARQ sheep with deer cerebrum represents sheep 3; C) VRQ/ARR with deer cerebrum sheep 5. D) VRQ/VRQ sheep with deer obex represents sheep 6; E) ARQ/ARQ with deer obex represents sheep 8 and 9; F) VRQ/ARR with deer obex represents sheep 10.