pgen.1009802.g001.tif (948.8 kB)
Association of the LIPG p.Asn396Ser variant with plasma lipids in humans.
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posted on 2021-09-20, 17:46 authored by Sumeet A. Khetarpal, Cecilia Vitali, Michael G. Levin, Derek Klarin, Joseph Park, Akhil Pampana, John S. Millar, Takashi Kuwano, Dhavamani Sugasini, Papasani V. Subbaiah, Jeffrey T. Billheimer, Pradeep Natarajan, Daniel J. RaderA-D. Association of LIPG p.Asn396Ser with plasma total cholesterol (A), HDL-C (B), LDL-C (C), and triglycerides (D) in the UK Biobank (UKBB) whole exome sequencing subset, UKBB genome-wide genotyping subset, Global Lipids Genetics Consortium (GLGC), and Million Veteran Program (MVP) cohorts, and a fixed-effects meta-analysis of these cohorts. Effect estimates after log-transformation for each lipid trait in standard deviation (S.D.) units and 95% confidence intervals are plotted.
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