pntd.0009583.g001.tif (1.52 MB)
Antitrypanosomal in vitro activity for racemic eflornithine and its enantiomers against three different T.b. gambiense strains.
figure
posted on 2021-07-12, 17:41 authored by Mikael Boberg, Monica Cal, Marcel Kaiser, Rasmus Jansson-Löfmark, Pascal Mäser, Michael AshtonIn vitro activity for racemic eflornithine (blue), L-eflornithine (green) and D-eflornithine (red) against T.b. gambiense strains a) STIB930, b) K03048 and c) 130R. Parasite growth values are shown as relative fluorescence in the AlamarBlue serial drug dilution assay. Dots represent observed experimental data, lines the model predictions and grey areas the 5th to 95th percentiles of the model prediction central values.
