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Analysis of recurrence-free survival (RFS) in patients with small-bowel cancer related to SMAD4 mutation.

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posted on 2021-05-20, 17:49 authored by Akiyoshi Tsuboi, Yuji Urabe, Shiro Oka, Akihiko Sumioka, Sumio Iio, Ryo Yuge, Ryohei Hayashi, Toshio Kuwai, Yasuhiko Kitadai, Kazuya Kuraoka, Koji Arihiro, Shinji Tanaka, Kazuaki Chayama

Patients with mutant SMAD4 had significantly poorer prognosis than those with wild-type SMAD4 (P = 0.04).

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    3CANOTCHPIKARIDAPCKRASwild-type SMAD 429 tumor specimensmismatch repair status evaluationEPsurvivalCREBBP1ATMBgenomic variantsclinicopathological featuresIHCsmall-bowel cancerssmall-bowel cancerPTCHSMAD 4 mutationscancer genomic analysisTPprognosisSMAD 4small-bowel cancer patients

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