(a) OS of patients with small-bowel cancer and mutations in TP53 (A), KRAS (B), PIK3CA (C), and SMAD4 (D). (b) DSS of patients with small-bowel cancer and mutations in TP53 (A), KRAS (B), PIK3CA (C), and SMAD4 (D). There were no significant differences in survival associated with any gene mutation.