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Additional file 8 of Piglet innate immune response to Streptococcus suis colonization is modulated by the virulence of the strain

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posted on 2021-12-20, 04:11 authored by Carlos Neila-Ibáñez, Louise Brogaard, Lola Pailler-García, Jorge Martínez, Joaquim Segalés, Mariela Segura, Peter M. H. Heegaard, Virginia Aragon
Additional file 8. Significant gene expression in spleen and liver after S. suis intranasal inoculation. Log2 of the individual values and mean (black bars) of the relative gene expression in spleen and liver in S. suis inoculated piglets. Piglets were intranasally inoculated with S. suis T15 (non-virulent, blue bars) or S10 (virulent, red bars), and necropsies were performed at 1 and 3 days post-infection. Gene expression was normalized relative to the PBS group. The values and means are shown for the indicated groups (challenge strain and time point) having at least one significant difference when compared to the PBS group. * indicates significant differences (P < 0.05) versus the PBS group. Differences between strains at the same time point are labelled with # and differences between time points for the same strain are labelled with +, P < 0.05, in both cases. n = 4 for each group. All expression values and significant differences can be found in Additional file 5.


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