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Additional file 6 of Systemic inflammation alters the neuroinflammatory response: a prospective clinical trial in traumatic brain injury

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posted on 2021-09-26, 03:16 authored by Philipp Lassarén, Caroline Lindblad, Arvid Frostell, Keri L. H. Carpenter, Mathew R. Guilfoyle, Peter J. A. Hutchinson, Adel Helmy, Eric Peter Thelin
Additional file 6. Description of data: Coefficients of linear mixed effect models, displayed as heatmaps. The colours of the heatmaps are graded such that red represents positive coefficients and blue represents negative coefficients. All coefficients are normalized using the quotient of their standard deviation and that of the dependent variable. Significant coefficients are highlighted with an asterisk. Independent variables are along the x-axis and the dependent variable for each model is the cytokine of the respective row on the y-axis in either (A) the brain extracellular fluid or (B) arterial blood. Differences in cytokines displayed between the two subfigures is due to insufficient data to generate all coefficients from the model.

Funding

Swedish Brain Foundation Karolinska Institutet Region Stockholm National Institute for Health Research Biomedical Research Centre, Cambridge (Neuroscience Theme; Brain Injury and Repair Theme) National Institute for Health Research (NIHR) NIHR Cambridge Biomedical Research Centre NIHR Global Health Research Group on Neurotrauma a European Union Seventh Framework Program grant (Collaborative European NeuroTrauma Effectiveness Research in TBI [CENTER-TBI]) Royal College of Surgeons of England Royal College of Surgeons of England Pump Priming Grant MRC/Royal of Surgeons of England Clinical Research Training Fellowship MRC Grant Swedish Society for Medical Research StratNeuro Stockholms Läns Landsting Karolinska Institute

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    Journal of Neuroinflammation

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