Additional file 6 of Alternative splicing of NF-YA promotes prostate cancer aggressiveness and represents a new molecular marker for clinical stratification of patients
Additional file 6: Suppl. Figure S6. Effect of NF-YA overexpression on tumor growth in vivo and analysis of NF-YA isoforms in PCa metastatic sites. (A) Volumes (mm3) of Empty, NF-YAs and NF-YAl xenograft tumors at the indicated time points. Data represent mean ± SEM (two-way ANOVA with Holm-Sidak's test: *p<0.05, **p<0.01, ns, not significant, n=8). (B) Images of xenograft tumors dissected from SCID Hairless Outbred (SHO®) mice after 5 weeks from s.c. injection. (C) Analysis of NF-YAs and NF-YAl transcripts in metastatic sites from PCa samples (GEO147250) and TCGA dataset (Prostate primary).