posted on 2021-09-26, 03:16authored byPhilipp Lassarén, Caroline Lindblad, Arvid Frostell, Keri L. H. Carpenter, Mathew R. Guilfoyle, Peter J. A. Hutchinson, Adel Helmy, Eric Peter Thelin
Additional file 4. Title of data: Timing of blood samples and cytokine pooling. Description of data: Illustrating the timing between microdialysis samples, blood compartment samples and recombinant human Interleukin 1 receptor antagonist (rhIL1ra) treatment. Microdialysis sampling (green) were pooled during 6 h epochs throughout the study. The rhIL1ra treatment was administered once daily to patients in the treatment arm (blue). Blood samples were taken one hour before and one hour after administration of rhIL1ra (or equivalent timing, but no drug, in the control group) (red).
Funding
Swedish Brain Foundation Karolinska Institutet Region Stockholm National Institute for Health Research Biomedical Research Centre, Cambridge (Neuroscience Theme; Brain Injury and Repair Theme) National Institute for Health Research (NIHR) NIHR Cambridge Biomedical Research Centre NIHR Global Health Research Group on Neurotrauma a European Union Seventh Framework Program grant (Collaborative European NeuroTrauma Effectiveness Research in TBI [CENTER-TBI]) Royal College of Surgeons of England Royal College of Surgeons of England Pump Priming Grant MRC/Royal of Surgeons of England Clinical Research Training Fellowship MRC Grant Swedish Society for Medical Research StratNeuro Stockholms Läns Landsting Karolinska Institute