Additional file 4 of STOML2 potentiates metastasis of hepatocellular carcinoma by promoting PINK1-mediated mitophagy and regulates sensitivity to lenvatinib

Additional file 4: Figure S2. STOML2 expression is upregulated in HCC cells, promotes HCC proliferation and inhibits apoptosis in vitro. (A–B) Expression of mRNA (A) and proteins (B) levels of STOML2 in different HCC cell lines. Significantly increased STOML2 levels were detected in HCC cell lines especially in those with higher invasive and metastatic capabilities cells (MHCC-97H and HCCLM3) compared with L02. (C–D) The effects of STOML2 gain- or loss-of-function on in vitro proliferation (C) and apoptosis (D) by colony formation assay and flow cytometric analysis. *P<0.05; **P<0.01; ***P<0.001; ns, no significance.