12885_2017_3123_MOESM4_ESM.jpg (283.15 kB)
Additional file 4: Figure S3. of Rapid eradication of colon carcinoma by Clostridium perfringens Enterotoxin suicidal gene therapy
figure
posted on 2017-02-13, 05:00 authored by Jessica Pahle, Lutz Menzel, Nicole Niesler, Dennis Kobelt, Jutta Aumann, Maria Rivera, Wolfgang WaltherInfluence of optCPE in vivo gene transfer on body weight. Body weight of Co7515* PDX bearing mice was measured during tumor growth inhibition. In all animals no systemic toxicities, such as body weight loss, were observed, which strongly indicates the safety of this gene therapeutic approach. (JPG 283 kb)