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Additional file 2 of MG53 suppresses tumor progression and stress granule formation by modulating G3BP2 activity in non-small cell lung cancer

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posted on 2021-09-15, 03:20 authored by Haichang Li, Pei-Hui Lin, Pranav Gupta, Xiangguang Li, Serena Li Zhao, Xinyu Zhou, Zhongguang Li, Shengcai Wei, Li Xu, Renzhi Han, Jing Lu, Tao Tan, Dong-Hua Yang, Zhe-Sheng Chen, Timothy M. Pawlik, Robert E. Merritt, Jianjie Ma
Additional file 2: Supplementary Figure S2. Knockout of MG53 results in elevated stress granule formation in mg53-/- lung. (A) The whole protein extracts from wild type and mg53-/- lung were subjected to western blot analysis with anti-MG53 and G3BP2 antibodies. GAPDH served as a loading control. (B) Representative images of IHC staining of G3BP2 (red) from WT and mg53-/- mice lungs. The nucleus was stained with DAPI (blue). Arrows indicate stress granules.

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