posted on 2021-05-08, 03:28authored byJordi Mayneris-Perxachs, Marina Cardellini, Lesley Hoyles, Jèssica Latorre, Francesca Davato, José Maria Moreno-Navarrete, María Arnoriaga-Rodríguez, Matteo Serino, James Abbott, Richard H. Barton, Josep Puig, Xavier Fernández-Real, Wifredo Ricart, Christopher Tomlinson, Mark Woodbridge, Paolo Gentileschi, Sarah A. Butcher, Elaine Holmes, Jeremy K. Nicholson, Vicente Pérez-Brocal, Andrés Moya, Donald Mc Clain, Rémy Burcelin, Marc-Emmanuel Dumas, Massimo Federici, José-Manuel Fernández-Real
Additional file 9: Figure S4. Associations of bacterial families with iron-related genes (discovery cohort, n = 35). Only significant correlations are coloured. Genes were measured by real time-PCR. Bacterial families with a significant positive association with serum ferritin concentrations are highlighted in dark red, whereas those with a significant negative association are highlighted in dark blue. ChREBP, carbohydrate response element binding protein; LCN2, Lipocailin 2; MitoNEET, Mitochondrial Inner NEET Protein; TFRC, Transferrin Receptor; SLC40A1, Solute Carrier Family 40 Member 1 (Ferroportin); TF, Transferrin; FTH1, Ferritin Heavy Chain 1; HAMP, Hepcidin Antimicrobial Peptide; FTL, Ferritin Light Chain; IRP1, Iron Regulatory Protein 1.
Funding
Horizon 2020 Framework Programme Instituto de Salud Carlos III