ppat.1009723.s007.tif (9.22 MB)
Additional anti-hACE2 IHC images.
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posted on 2021-07-02, 17:38 authored by Daniel J. Rawle, Thuy T. Le, Troy Dumenil, Kexin Yan, Bing Tang, Wilson Nguyen, Daniel Watterson, Naphak Modhiran, Jody Hobson-Peters, Cameron Bishop, Andreas SuhrbierExamples of anti-hACE2 IHC (brown staining) in mouse lung alveolar epithelial cells, additional to Fig 3G. Staining was evident in mouse lungs transduced with hACE2-lentivirus, and no staining was evident in mock transduced mouse lung.
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N 30D N 31K F 83Ymouse SARS-CoV -2 infectionIntrapulmonary hACE 2-lentivirus tr...H 353K substitutionsCOVID -19 patientsSARS-CoV -2 researchACE 2-lentiviral transductionnon-permissive cell linesreceptor interactions SARS-CoV -2hACE 2-lentivirus transduction systemACE 2-lentivirus systemSARS-CoV -2 replicationIII interferon responsesILIFNARvirus replication-28RAvivo SARS-CoV -2 infection modelsC 57BL micehACE 2-lentivirus transductionmouse ACE 2mouse model development
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