Data of 84 key genes involved in inflammatory and immune functions are plotted. Forty of the 84 genes are differentially expressed with greater than twofold upregulation (greater than a twofold change, 33 genes) or downregulation (less than a 0.5-fold change, 7 genes), as well as significant P-values to indicate differential expression levels (P<0.05, t-test) between the cochleae of 12-month-old vs. 6–7-week-old mice (young control mice). The x-axis indicates Log2 (fold change of 12-month-old mice/young control mice) showing the relative expression levels. The y-axis represents–Log10 (P-value) to assess significant differences between the two groups (n = 3 for each gene in the 12-month-old and young control mice).