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Figure S1 - A BAC-Based Transgenic Mouse Specifically Expresses an Inducible Cre in the Urothelium

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posted on 2012-04-09, 01:49 authored by Tian Huai Shen, Nataliya Gladoun, Mireia Castillo-Martin, Dennis Bonal, Josep Domingo-Domenech, Daniel Charytonowicz, Carlos Cordon-Cardo

qRT-PCR analysis of relative expression levels of Bcl9l, Cxcr5, and Foxr1 in the bladders of Wt (set to 1) and TgUICBAC mice. Mouse Gapdh expression level was used as control. Refer to “Method” for more detail. In a brief summary, Bcl9l showed a 2.2-fold increase in male (p = 0.014) and 1.8-fold increase in female (p = 0.02); Cxcr5 showed a 20.8-fold increase in male (p = 0.013) and 21.7-fold increase in female (p = 0.002); and Foxr1 showed a 40.0-fold increase in male (p = 0.033) and 43.0-fold increase in female (p = 0.006). No significant differences were observed between male and female TgUICBAC mice in transcript levels of the three genes.