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gs_file.zip (475.83 kB)
scDRS_data_release_092121
Data files used for reproducing main results of the paper (initial submission).
- gold_standard_gs.zip: drug targets and Mendelian disease genes, consistent with Supp. Table.
- score_file.zip: (1) scDRS score files for TMS FACS + hepatocyte signatures, (2) scDRS score files for Zeisel et al. 2015 (brain traits + inferred spatial coordinates).
- gene_annotation.zip: (1) MAGMA p-values for all genes and the 74 diseases/traits, (2) mouse-human homologs.
- gs_file.zip: (1) .gs file for the 74 diseases/traits (magma_10kb_1000.74_traits.gs), (2) batch .gs files for the 74 diseases/traits (magma_10kb_1000.74_traits.gs.batch).
- single_cell_data.zip: (1) reprocessed TMS FACS T cell data (./tms_proc/tcell.facs.annot.h5ad), (2) reprocessed TMS FACS hepatocytes data (./tms_proc/hep.facs_annot.h5ad), (3) Zeisel et al. 2015 processed data ./zeisel_2015
- sumstats.zip: GWAS summary statistics of the 74 diseases/traits.
- tabula_muris_senis.zip: TMS FACS scRNA-seq data.
- supp_table.zip: disease information (trait_info.tsv), consistent with Supp. Table.
