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In vitro activity of ceftazidime/avibactam, amikacin, colistin and tigecycline against Klebsiella pneumoniae carbapenemase-producing K. pneumoniae.

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posted on 2021-10-14, 17:42 authored by Fangzhou Wang, Qian Zhou, Xiuwen Yang, Yan Bai, Junchang Cui

In vitro activity of ceftazidime/avibactam, amikacin, colistin and tigecycline against Klebsiella pneumoniae carbapenemase-producing K. pneumoniae.

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    susceptibility testing suggestedminimum inhibitory concentrationhuman health worldwideexhibit better effectagar dilution methodbroth dilution methodtigecycline displayed indifferenceamikacin displayed synergism1 × 10klebsiella pneumoniae synergistic activities testing5 pneumoniae synergistic activitiescheckerboard methodhinton brothvitro k antibacterial activitiessingle drugoptimize multidrugoften inadequatemhb ).major threatline choicekill experimentkill assaysinfection managementdifferent mechanisms2 hospitals14 %).

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