Source Data Files.zip (15.4 MB)
Targeted Small Molecule Inhibitors Blocking the Cytolytic Effects of Pneumolysin and Homologous Toxins
Version 3 2024-03-15, 19:25
Version 2 2024-03-05, 18:53
Version 1 2024-01-22, 19:09
dataset
posted on 2024-03-15, 19:25 authored by Umer Bin Abdul AzizUmer Bin Abdul Aziz, Ali Saoud, Marcel Bermudez, Maren Mieth, Amira Atef, Thomas Rudolf, Christoph Arkona, Timo Trenkner, Christoph Böttcher, Kai Ludwig, Angelique Hoelzemer, Andreas C. Hocke, Gerhard WolberGerhard Wolber, Jörg RademannJörg RademannThis work established CDC toxins as small molecule protein targets by using the UDP sequence of the cholesterol binding domain as binding site.
Funding
SFB 765: Multivalency as Chemical Organisation and Action Principle: New Architectures, Functions and Applications
Deutsche Forschungsgemeinschaft
Find out more...SFB 1349: Fluorine-Specific Interactions: Fundamentals and Functions
Deutsche Forschungsgemeinschaft
Find out more...