Table_1.xls (5.5 kB)
Pneumolysin allele determination by sequencing of ply genes was performed from the 6 isolates used in this study.
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posted on 2015-08-28, 03:30 authored by Diana Fatykhova, Anne Rabes, Christoph Machnik, Kunchur Guruprasad, Florence Pache, Johanna Berg, Mario Toennies, Torsten T. Bauer, Paul Schneider, Maria Schimek, Stephan Eggeling, Timothy J. Mitchell, Andrea M. Mitchell, Rolf Hilker, Torsten Hain, Norbert Suttorp, Stefan Hippenstiel, Andreas C. Hocke, Bastian OpitzThe first row refers to amino acid positions. The second row shows allele 1 PLY expressed in S. pneumoniae D39 [21]. The amino acid polymorphisms in the clinical isolates are highlighted. Deletion of an amino acid is represented by the abbreviation DEL. Serotype 1 and 8 pneumococci express an allele 5 PLY as previously shown [21].
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8 Pneumococci Evadepneumococcal infectiontoxin8 strainshaemolytic pneumolysinSerotype 1pneumococcal serotypes differentially90 serotypeslung tissueilhaemolytic pneumolysinsvirulence factorNLRP 3 inflammasomeserotype 1 pneumococciHuman Lung Tissue Streptococcus pneumoniae9 N pneumococcimlstlung organ culture system
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