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UKB_telomere_gwas_summarystats.tsv.gz (438.54 MB)

UKB_telomere_gwas_summarystats.tsv.gz

dataset

posted on 2021-06-16, 11:02 authored by Veryan Codd, Qingning WangQingning Wang, Elias Allara, Crispin Musicha, Stephen Kaptoge, Svetlana Stoma, tao jiang, Stephen E. Hamby, Peter S. Braund, Vasiliki Bountziouka, Charley A. Budgeon, Matthew Denniff, Chloe Swinfield, Manolo Papakonstantinou, Shilpi Sheth, Dominika E. Nanus, Sophie C. Warner, Minxian Wang, Amit V. Khera, James Eales, Willem H. Ouwehand, John R Thompson, Emanuele Di Angelantonio, Angela M. Wood, Adam S. Butterworth, John N. Danesh, Christopher P. Nelson, Nilesh J. Samani

Codd, Veryan, et al. "Polygenic basis and biomedical consequences of telomere length variation." medRxiv (2021).

Column header	Description
variant_id	The identifier of the variant : rsID or genome coordinate i.e. rs7329174 or 1:1235_C_G
p_value	The p-value of the variant/trait association
chromosome	The chromosome that the variant is located on
base_pair_location	The base pair location of the variant
effect_allele	The effect allele of the variant
other_allele	The non-effect allele
effect_allele_frequency	Frequency of the effect allele
beta	The beta of the variant/trait association
standard_error	The standard error of the beta

Analysis was restricted to variants with MAF ≥ 0.1% and INFO score ≥ 0.3, and was conducted using BOLT-LMM, adjusting for age, gender, array, and the first 10PCs.