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Supplementary File S08 - Mapping of CHAGASTOPE-v1 data to T cruzi proteins.zip (61.88 MB)
Supplementary Materials for: The Chagas Antigen and Epitope Atlas
Version 2 2023-01-17, 15:20
Version 1 2022-08-19, 15:23
dataset
posted on 2023-01-17, 15:20 authored by Fernán AgüeroFernán Agüero, Alejandro Ricci, Leonel Bracco
The Chagas Antigen and Epitope Atlas contains experimentally-derived information on the antigenicity of Trypanosoma cruzi peptides. Antigenicity was measured on peptide arrays assayed with serum samples from Chagas disease subjects and matched negative controls.
High-density peptide arrays with custom designs were to display peptides derived from two complete T. cruzi proteomes.
Sampling of subjects from diverse human populations complements the antigenicity information of proteins and peptides with seroprevalence information across the Americas.
Funding
HIGH-THROUGHPUT EPITOPE DISCOVERY: USE OF NEXT-GENERATION PEPTIDE CHIPS FOR FAST IDENTIFICATION AND FINE MAPPING OF DIAGNOSTIC AND PROGNOSTIC MARKERS FOR CHAGAS DISEASE
National Institute of Allergy and Infectious Diseases
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